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Table 4 Rates of overall survival and locoregional recurrence rates after complete resection in pN2 NSCLC

From: The emerging outcome of postoperative radiotherapy for stage IIIA(N2) non-small cell lung cancer patients: based on the three-dimensional conformal radiotherapy technique and institutional standard clinical target volume

Author Year Stage No. of patients 5-y OS (%) 5-y LRR rates (%)
S S + PORT S S + PORT
SEER [7] 2006 pN2 1987 20 27 NS
ANITA [8] 2008 pN2 106(observation) 16.6 21.3 42.1* 22.1*
118(chemotherapy) 34 47.4 25.7* 14.6*
Zou et al. [9] 2010 pN2 183 22.2 30.5 66 27
Scotti et al. [10] 2010 pN2 175 NS 44 20
Dai et al. [11] 2011 IIIA-N2 221 30.6 36.6 53 36
Mantovani et al. [12] 2013 pN2 66 NS 37 NS 28
Shen et al. [13] 2014 IIIA-N2 135 27.5 37.9 49.3* 27.3*
  1. Note: *indicates crude LRR rates. Abbreviations: NS = not stated, OS = overall survival, LRR = locoregional recurrence, S = surgery, S + PORT = surgery plus postoperative radiotherapy, SEER = Surveillance, Epidemiology, and End Results, ANITA = Adjuvant Navelbine International Trialist Association.