The emerging outcome of postoperative radiotherapy for stage IIIA(N2) non-small cell lung cancer patients: based on the three-dimensional conformal radiotherapy technique and institutional standard clinical target volume

Table 4 Rates of overall survival and locoregional recurrence rates after complete resection in pN2 NSCLC

Author	Year	Stage	No. of patients	5-y OS (%)		5-y LRR rates (%)
Author	Year	Stage	No. of patients	S	S + PORT	S	S + PORT
SEER [7]	2006	pN2	1987	20	27	NS
ANITA [8]	2008	pN2	106(observation)	16.6	21.3	42.1^*	22.1^*
ANITA [8]	2008	pN2	118(chemotherapy)	34	47.4	25.7^*	14.6^*
Zou et al. [9]	2010	pN2	183	22.2	30.5	66	27
Scotti et al. [10]	2010	pN2	175	NS		44	20
Dai et al. [11]	2011	IIIA-N2	221	30.6	36.6	53	36
Mantovani et al. [12]	2013	pN2	66	NS	37	NS	28
Shen et al. [13]	2014	IIIA-N2	135	27.5	37.9	49.3^*	27.3^*

Note: *indicates crude LRR rates. Abbreviations: NS = not stated, OS = overall survival, LRR = locoregional recurrence, S = surgery, S + PORT = surgery plus postoperative radiotherapy, SEER = Surveillance, Epidemiology, and End Results, ANITA = Adjuvant Navelbine International Trialist Association.

ISSN: 1471-2407