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Table 1 Patient characteristics

From: The emerging outcome of postoperative radiotherapy for stage IIIA(N2) non-small cell lung cancer patients: based on the three-dimensional conformal radiotherapy technique and institutional standard clinical target volume

Characteristics PORT Non-PORT P-value
No. (%) No. (%)
Patients (N) 70 287  
Age (yr)    0.55
 ≤60 43 (61.4) 165 (57.5)  
 >60 27 (38.6) 122 (42.5)  
Gender    0.03
 Male 35 (50) 184 (64.1)  
 Female 35 (50) 103 (35.9)  
Smoking history*    0.004
 Never/light 46 (65.7) 134 (46.7)  
 Current/heavy 24 (34.3) 153 (53.3)  
Clinical N status    0.45
 cN0,1 35 (50) 158 (55.1)  
 cN2 35 (50) 129 (44.9)  
Pathologic T stage    0.05
 pT1 15 (21.4) 65 (22.7)  
 pT2 53 (75.7) 186 (64.8)  
 pT3 2 (2.9) 36 (12.5)  
Type of surgery    0.01
 Lobectomy 67 (95.7) 244 (85.0)  
 Sleeve lobectomy 3 (4.3) 9 (3.1)  
 Pneumonectomy 0 34 (11.9)  
Tumor location    0.13
 RUL 26 (37.1) 73 (25.4)  
 RML 9 (12.9) 24 (8.4)  
 RLL 12 (17.1) 50 (17.4)  
 LUL 14 (20.0) 90 (31.4)  
 LLL 9 (12.9) 50 (17.4)  
Histology    0.56
 Adenocarcinoma 47 (67.2) 169 (58.9)  
 Squamous 15 (21.4) 85 (29.6)  
 Adenosquamous 6 (8.6) 22 (7.7)  
 Large cell 1 (1.4) 9 (3.1)  
 Pleomorphic 1 (1.4) 2 (0.7)  
N of positive nodes    0.04
 ≤4 30 (42.9) 162 (56.4)  
 >4 40 (57.1) 125 (43.6)  
LNR    0.002
 ≤20% 22 (31.4) 150 (52.3)  
 >20% 48 (68.6) 137 (47.7)  
Involved N2 stations    0.32
 Single 31 (44.3) 146 (50.9)  
 Multiple 39 (55.7) 141 (49.1)  
Cycles of POCT    0.08
 <4 12 (17.1) 78 (27.2)  
 ≥4 58 (82.9) 209 (72.8)  
Subsequent EGFR-TKI therapy   0.004
 Yes 22 (31.4) 47 (16.4)  
 No/unknown 48 (68.6) 240 (83.6)  
  1. Note: *Smoking history was categorized as never/light ex-smokers (<100 cigarettes smoked in the lifetime or smoked ≤10 pack-years, having stopped for ≥15 years) or, the current/heavy ex-smokers.
  2. Abbreviations: LNR = lymph node ratio (defined as the ratio of metastatic to examined lymph nodes), RUL = right upper lobe, RML = right middle lobe, RLL = right lower lobe, LUL = left upper lobe, LLL = left lower lobe, PORT = postoperative radiotherapy, POCT = postoperative chemotherapy, EGFR-TKI = epidermal growth factor receptor tyrosine kinase inhibitor.