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Table 2 The clinical characteristics in 8 patients who died before or during first cycle of chemotherapy

From: Management and prognosis of patients with brain metastasis from gestational trophoblastic neoplasia: a 24-year experience in Peking union medical college hospital

Case No.

Age(yrs)

FIGO score

AP

Interval time (mons)

Pretreatment serum β-hCG level

Site of metastases

Chemotherapy

Cause of death

1

53

15

Abortion

180

99000.0

Lung/brain/kidney

Not done

Brain hemorrhage, respiratory failure

2

30

21

Abortion

10

906720.0

Lung/brain/liver/kidney

Not done

Septic shock

3

31

8

Mole

32

80.0

Lung/brain

5-FU*1d

Brain herniation

4

25

12

Mole

27

57380.0

Lung/brain

EMA*1

Brain herniation

5

32

12

Term

6

200000.0

Lung/brain/kidney

FAEV*2d

Respiratory failure, cardiac arrest

6

36

13

Mole

56

9306.0

Lung/brain/bladder

FAEV*1d

Multiple organ failure

7

26

15

Term

3

60436.5

Lung/brain

FAEV*3d

Brain stem hemorrhage

8a

33

17

Mole

36

2400.0

Lung/brain

FAEV*4d

Brain herniation

  1. AP: antecedent pregnancy; EMA: etoposide, methotrexate, dactinomycin; FAEV: floxuridine, dactinomycin, etoposide, and vincristine; 5-FU: fluorouracil.
  2. a recurrent choriocarcinoma.