From: Mammographic microcalcifications and breast cancer tumorigenesis: a radiologic-pathologic analysis
(a) Categorical variables | Microcalcifications | Test statistic | ||||
---|---|---|---|---|---|---|
No | Yes | |||||
n | (%) | n | (%) | χ2 | p-value | |
Recurrence | 1.28 | 0.258 | ||||
Yes | 21 | (52.5) | 19 | (47.5) | ||
No | 287 | (61.6) | 179 | (38.4) | ||
Histology | 15.1 | 0.001 * | ||||
Ductal | 357 | (59.1) | 247 | (40.9) | ||
Lobular | 58 | (82.9) | 12 | (17.1) | ||
Other | 44 | (63.8) | 25 | (36.2) | ||
Lymphovascular Invasion | 1.98 | 0.159 | ||||
Yes | 72 | (57.6) | 53 | (42.4) | ||
No | 334 | (64.9) | 181 | (35.1) | ||
Node Status | 0.08 | 0.782 | ||||
Positive | 134 | (62.3) | 81 | (37.7) | ||
Negative | 287 | (63.8) | 163 | (36.2) | ||
Tumor Grade | 5.74 | 0.057 | ||||
1 | 133 | (69.3) | 59 | (30.7) | ||
2 | 192 | (60.2) | 127 | (39.8) | ||
3 | 122 | (58.7) | 86 | (41.3) | ||
Density | 12.32 | 0.031 | ||||
Almost entirely fatty | 164 | (65.1) | 88 | (34.9) | ||
Scattered | 44 | (61.1) | 28 | (38.9) | ||
Very dense | 10 | (58.8) | 7 | (41.2) | ||
Extremely dense | 16 | (66.7) | 8 | (33.3) | ||
Heterogeneously dense | 23 | (40.4) | 34 | (59.7) | ||
Other | 17 | (60.7) | 11 | (39.3) | ||
Bilaterality | 0.18 | 0.669 | ||||
Yes | 6 | (50.0) | 6 | (50.0) | ||
No | 320 | (60.4) | 210 | (39.6) | ||
Architectural Distortion | 0.81 | 0.369 | ||||
Yes | 47 | (56.0) | 37 | (48.1) | ||
No | 268 | (61.9) | 165 | (38.1) | ||
Focality | 4.04 | 0.044 | ||||
Multifocal/Multicentric | 49 | (52.1) | 45 | (47.9) | ||
Unifocal | 271 | (63.9) | 153 | (36.1) | ||
Menopausal Status | 8.86 | 0.012 | ||||
Pre | 111 | (59.0) | 77 | (41.0) | ||
Peri | 9 | (36.0) | 16 | (64.0) | ||
Post | 331 | (64.1) | 185 | (35.9) | ||
Diabetes | 0.00 | 0.999 | ||||
Yes | 26 | (60.5) | 17 | (39.5) | ||
No | 294 | (60.1) | 195 | (39.9) | ||
Family History | 1.66 | 0.198 | ||||
Yes | 91 | (56.5) | 52 | (43.5) | ||
No | 144 | (63.6) | 111 | (36.4) | ||
Children | 4.33 | 0.115 | ||||
Yes | 156 | (62.7) | 93 | (37.3) | ||
Yes-after age 30 | 25 | (50.0) | 25 | (50.0) | ||
No | 59 | (53.6) | 51 | (46.4) | ||
HER-2 | 12.9 | <0.001 | ||||
Positive | 48 | (47.1) | 54 | (52.9) | ||
Negative | 399 | (66.2) | 204 | (33.8) | ||
ER | 0.36 | 0.549 | ||||
Positive | 89 | (59.7) | 60 | (40.3) | ||
Negative | 375 | (62.8) | 222 | (37.2) | ||
PR | 1.42 | 0.233 | ||||
Positive | 150 | (59.1) | 104 | (40.9) | ||
Negative | 314 | (63.8) | 178 | (34.9) | ||
(b) Continuous Variables | Microcalcification | Test Statistic | ||||
No | Yes | |||||
Mean | SD | Mean | SD | t | p-value | |
Age | 59.0 | (13.2) | 57.4 | (12.3) | 1.67 | 0.100 |
Tumor Size | 2.2 | (1.8) | 2.5 | (2.1) | −1.58 | 0.115 |