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Table 7 Immunohistochemical findings of hormone receptors and pancreatic polypeptide

From: Gangliocytic paraganglioma: a multi-institutional retrospective study in Japan

 

Estrogen receptor

Progesterone receptor

Pancreatic polypeptide

Immunoreactivity in the epithelioid cells of GP

3 / 12 (25.0%)

11 / 12 (91.7%)

11 / 12 (91.7%)

Immunoreactivity in the NET G1

0 / 6 (0%)

0 / 6 (0%)

0 / 6 (0%)

P value (Chi-Square test)

P = 0.180

P < 0.001

P < 0.001

  1. GP: Gangliocytic paraganglioma, NET: neuroendocrine tumor.
  2. Legend: Duodenal neuroendocrine tumor (NET) G1 except for gangliocytic paraganglioma (GP) showed completely negative reactivity for hormone (estrogen and progesterone) receptors and pancreatic polypeptide. Statistically, GP showed significantly higher positive reactivity for progesterone receptor and pancreatic polypeptide (Chi-square test: P < 0.05 for each).