Figure 4

Platelets act as a chemoattractant to enhance ovarian cancer cell migration. Effect of platelets on migration and chemotaxis assays performed in SKOV3, UCI101 and primary cultured cancer cells obtained from ovarian ascites (Patient 10). A, B and C shows the number of cells that migrated under “Control” (no platelets added), “Upper” (platelets added within the cells) or “Lower” conditions (platelets added in the lower chamber) N = 3 for cell lines, **p < 0.01 relative to control, ANOVA with Bonferroni as Post- test.