Figure 1
From: STAT3 is involved in miR-124-mediated suppressive effects on esophageal cancer cells
MiR-124 targets STAT3 gene in esophageal cancer cells. (A) Relative luciferase activity of the indicated STAT3 reporter construct in both esophageal cancer cell lines, co-transfected with miR-124 mimic or scramble mimic, is shown; (B) Quantitative RT-PCR assays were performed to detect the expression of STAT3 upon transfection with miR-124 mimic or scramble mimic (normalized to GAPDH); (C) Western blot analysis showed the expression levels of STAT3, p-STAT3, Bcl-xL and MMP-9 proteins in esophageal cancer cells upon transfection with miR-124 mimic. **P < 0.01.