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Table 3 Multivariate cox proportional hazards regression model to predict progression-free survival from chemotherapy start by FRS2α intensity level

From: The impact of FGFR1 and FRS2α expression on sorafenib treatment in metastatic renal cell carcinoma

Variable

Level

Hazard ratio

95% Hazard ratio confidence limits

Probability > Chi square test

Treatment arm

Sorafenib vs. Sorafenib + interferon

1.915

0.850

4.314

0.1171

ECOG Status

1 vs. 0

4.651

1.508

14.341

0.0075

Anemia

Yes vs. No

1.831

0.628

5.342

0.2683

FRS2α Intensity

(3 or 4) vs. 1

7.318

1.531

34.971

0.0126

2 vs. 1

2.959

0.765

11.449

0.1161

  1. ECOG, Eastern Cooperative Oncology Group; FRS2α, fibroblast growth factor receptor substrate 2 alpha.