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Table 2 Clinico-pathological features of HCC in relation to GEP DNA copy number

From: Copy number gain of granulin-epithelin precursor (GEP) at chromosome 17q21 associates with overexpression in human liver cancer

 

GEP DNA copy number

 

HCC features

No gain

Gain

P 1

Venous infiltration

   

Absent

19

7

0.397

Present

29

5

 

Tumour size

   

Small (≤5 cm)

10

3

1.000

Large (>5 cm)

38

9

 

pTNM stage

   

Early stage (I-II)

31

9

0.732

Late stage (III-IV)

17

3

 

Edmondson grade

   

Well differentiation

41

10

1.000

Poor differentiation

7

2

 

Gender

   

Male

42

7

0.055

Female

6

5

 

Age

   

Young (≤60)

37

6

0.133

Elderly (>60)

11

6

 

Serum AFP level

   

Low (≤20 ng/mL)

21

1

0.052

High (>20 ng/mL)

27

11

 

HBV status (HBsAg)

   

Negative

4

5

0.015

Positive

44

7

 
  1. 1Pearson chi-square test with Yates continuity correction.
  2. Abbreviations: AFP alpha-fetoprotein, HBV hepatitis B virus, HBsAg hepatitis B surface antigen.