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Table 4 Grade 3 -5 adverse events of interest with bevacizumab ( N = 77)

From: Capecitabine and irinotecan with bevacizumab 2-weekly for metastatic colorectal cancer: the phase II AVAXIRI study

Adverse event

Grade 3

Grade 4

Grade 5

N

%

N

%

N

%

Hypertension

2

2.6

0

0

0

0

Proteinuria

1

1.3

0

0

0

0

Gastrointestinal perforation

1

1.3

1

1.3

1

1.3

Arterial thrombosis

1

1.3

0

0

0

0

Deep vein thrombosis

1

1.3

1

1.3

0

0

Pulmonary thromboembolism

2

2.6

8

10.4

0

0