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Table 1 IC 50 values of GF on different cancer cell lines

From: The natural compound Guttiferone F sensitizes prostate cancer to starvation induced apoptosis via calcium and JNK elevation

Cell line

Cell type

IC50(μM)

LNCaP

Prostate Cancer

5.17 ± 0.20

LNCaP

Prostate Cancer

20.00 ± 0.59 *

PC-3

Prostate Cancer

12.64 ± 3.01

Hep G2

Hepatocellular Carcinoma

32.93 ± 1.56

HeLa

Cervical Cancer

13.13 ± 1.32

CNE

Nasopharyngeal Carcinoma

17.97 ± 1.30

  1. The IC50 values were determined in serum withdraw medium using MTT assay. GF inhibits the growth of different cancer cell lines selectively. 1× 104 cells were plated in 96-well plates per well and treated with different dose of GF for 48 h. *The IC50s were obtained in cells under complete medium. Values are presented as mean ± s.e.m. of three independent experiments.