Skip to main content

Table 1 Association between AF-6/afadin immunoreactivity and clinicopathological parameters in 90 uterine endometrial cancers

From: Loss of AF-6/afadin induces cell invasion, suppresses the formation of glandular structures and might be a predictive marker of resistance to chemotherapy in endometrial cancer

AF-6/afadin immunoreactivity
Uterine endometrial cancer Positive (n = 51) Negative (n = 39) Pvalue
Mean age (range) 55.9 (32–83) 58.6 (28–80) 0.41
Histological type  
Endometrioid 51 (100%) 34 (87.2%)
Serous 0 3 (7.7%)
Clear 0 2 (5.1%) 0.21
Endometrioid adenocarcinoma Positive (n = 51) Negative (n = 34) P value
Histological grade  
1 38 (74.5%) 11 (32.4%)
2 11(21.6%) 13(38.2%)
3 2 (3.9%) 10 (29.4%) P < 0.01
Myometrial invasion  
No invasion 14 (27.5%) 1 (2.9%)
Less than half 26 (51.0%) 15 (44.1%)
More than half 11 (21.6%) 18 (52.9%) P < 0.01
Lymph node metastasis  
Negative 48 (94.1%) 30 (88.2%)
Positive 3 (5.9%) 4 (11.8%) 0.57
Stage  
I 37 (72.5%) 25 (73.5%)
II 7 (13.7.8%) 2 (5.9%)
III 6 (11.8%) 6 (17.6%)
IV 1 (2.0%) 1 (2.9%) 0.82
  1. Cases with H-score > 50 are positive.