Table 1 Association Between STYK1 Expression and Clinicopathologic Characteristics of CRC Patients in the Study Cohort
From: Serine threonine tyrosine kinase 1 is a potential prognostic marker in colorectal cancer
Characteristics | No. of | STYK1 expression | |||
|---|---|---|---|---|---|
patients (%) | Low (%) | High (%) | P valuea | ||
(n = 353) | (n = 213) | (n = 140) | |||
Age (years) | 0.783 | ||||
<60 | 93 (26.3) | 55 (25.8) | 38 (27.1) | ||
≥60 | 260 (73.7) | 158 (74.2) | 102 (72.9) | ||
Sex | 0.403 | ||||
Female | 166 (47.0) | 104 (48.8) | 62 (44.3) | ||
Male | 187 (53.0) | 109 (51.2) | 78 (55.7) | ||
Tumor location | 0.908 | ||||
Rectum | 155 (43.9) | 93 (43.7) | 62 (44.3) | ||
Colon | 198 (56.1) | 120 (56.3) | 78 (55.7) | ||
Differentiation grade | 0.030 | ||||
Well | 33 (9.3) | 27 (12.7) | 6 (4.3) | ||
Moderate | 256 (72.5) | 149 (70.0) | 107 (76.4) | ||
Poor | 64 (18.2) | 37 (17.3) | 27 (19.3) | ||
Tumor size (cm) | 0.950 | ||||
<5 | 152 (43.1) | 92 (43.2) | 60 (42.9) | ||
≥5 | 201 (56.9) | 121 (56.8) | 80 (57.1) | ||
Local invasion | 0.055 | ||||
T1-T2 | 48 (13.6) | 35 (16.4) | 13 (9.3) | ||
T3-T4 | 305 (86.4) | 178 (83.6) | 127 (90.7) | ||
Lymph node metastasis | 0.004 | ||||
N0 | 209 (59.2) | 140 (65.7) | 69 (49.3) | ||
N1 | 108 (30.6) | 58 (27.2) | 50 (35.7) | ||
N2 | 36 (10.2) | 15 (7.1) | 21 (15.0) | ||
TNM stage | 0.007 | ||||
I | 43 (12.2) | 31 (14.6) | 12 (8.6) | ||
II | 166 (47.0) | 109 (51.2) | 57 (40.7) | ||
III | 144 (40.8) | 73 (34.2) | 71 (50.7) | ||
Death | <0.001 | ||||
No | 211 (59.8) | 150 (70.4) | 61 (43.6) | ||
Yes | 142 (40.2) | 63 (29.6) | 79 (56.4) | ||