| ||||||
---|---|---|---|---|---|---|
Ent | Reagent | Prod. | Yield (%) | |||
R1 | R2 | R3 | X | |||
1 | Ph | Me | Me | O | 4c | 99 |
2 | Ph | OCH2CH3 | Me | S | 4d | 93 |
3 | Ph | Me | Me | S | 4e | 83 |
4 | 4-Cl-Ph | OCH2CH3 | Me | O | 4f | 87 |
5 | 4-Cl-Ph | OCH2CH3 | Me | S | 4h | 80 |
6 | 4-Cl-Ph | Me | Me | S | 4i | 77 |
7 | 3-OH-Ph | OCH2CH3 | Me | O | 4j | 98 |
8 | 3-OH-Ph | Me | Me | O | 4k | 80 |
9a | 3-OH-Ph | OCH2CH3 | Me | S | Mon | 93 |
10 | 3-OH-Ph | Me | Me | S | 4m | 88 |
11 | 2-OH-Ph | OCH2CH3 | Me | O | 4n | 84 |
12 | 2-OH-Ph | Me | Me | O | 4o | 80 |
13 | 2-OH-Ph | OCH2CH3 | Me | S | 4p | 84 |
14 | 2-OH-Ph | Me | Me | S | 4q | 90 |
15 | 3-NO2-Ph | OCH2CH3 | Me | O | 4r | 96 |
16 | 3-NO2-Ph | OCH2CH3 | Me | S | 4t | 86 |
17 | 3-NO2-Ph | Me | Me | S | 4u | 86 |
18 | 2-NO2-Ph | OCH2CH3 | Me | O | 4v | 70 |
19 | 2-NO2-Ph | Me | Me | O | 4x | 60 |
20 | 2-NO2-Ph | Me | Me | S | 4z | 60e |
21 | 4-OH-3-MeO-Ph | OCH2CH3 | Me | O | 4ba | 98 |
22 | 4-OH-3-MeO-Ph | OCH2CH3 | Me | S | 4bc | 85 |
23 | 4-OH-3-MeO-Ph | Me | Me | S | 4bd | 85 |
24 | H | OCH2CH3 | Me | O | 4be | 96 |
25 | Me | Me | Me | O | 4bj | 66 |
26 | Me | OCH2CH3 | Me | S | 4bk | 70 |
27 |
| OCH2CH3 | Me | O | 4bm | 87 |
28 |
| Me | Me | O | 4bn | 79 |
29b |
| OCH2CH3 | Me | S | 4bo | 70 |
30 |
| Me | Me | S | 4bp | 71 |
31 | 3-OH-Ph |
| O | 4bq | 60 | |
32c | 3-OH-Ph |
| S | 4br | 72 | |
33 | 3-OH-Ph |
| O | 4bs | 70 | |
34d | 3-OH-Ph |
| S | 4bt | 70 | |
35 |
| OCH2CH3 | Me | O | 4bu | 66f |
36 |
| Me | Me | S | 4bv | 50f |
37 |
| OCH2CH3 | Me | S | 4bx | 42f |
38 |
| Me | Me | O | 4by | 83 |