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Figure 3 | BMC Cancer

Figure 3

From: Remodeling of extracellular matrix by normal and tumor-associated fibroblasts promotes cervical cancer progression

Figure 3

Effect of fibroblasts on the proliferation of CSCC7 cells. CSCC7 cells grew much faster in the presence of normal fibroblasts than alone 48 hours after seeding (A). Culture media of normal fibroblasts enhanced the proliferation of CSCC7 tumor cells, indicating the presence of a yet unidentified growth stimulatory compound produced by normal fibroblasts (B), whereas the culture media of tumor associated fibroblasts exerted no effect (C). Factors produced by the tumor cells did not affect the proliferation of fibroblasts (B, C). CSCC7 control cells on chart B and C are taken from two independent experiments. Stars indicate significance: ***p < 0.0001. Scale bars correspond to 100 μm.

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