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Figure 4 | BMC Cancer

Figure 4

From: Vascular dysfunction and increased metastasis of B16F10 melanomas in Shb deficient mice as compared with their wild type counterparts

Figure 4

Proximity of CD8+ T cells with vascular structures. Cryosections of subcutaneous B16F10 melanomas were stained for CD8+ (red) and VE-cadherin (green). Pictures were taken at 20X (for statistical analysis) or 40X (for representative image) original magnification and the numbers of CD8+ cells immediately adjacent (direct contact) to VE-cadherin positive cells were scored in percent of total CD8+ cells for each host genotype present in the images. Representative images and statistics are shown as percent adjacent CD8+ cells (means ± SEM) for 4 tumors each genotype (5 images each tumor).

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