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Table 3 Test statistics for basaloid histologic subtype and p16 INK4a immunostaining to predict HR-HPV positivity in pSCC

From: The role of histologic subtype, p16INK4a expression, and presence of human papillomavirus DNA in penile squamous cell carcinoma

Test ppV (%) Sensitivity (%) Specificity (%)
Basaloid histologic subtype 40 11 95
Any positivity for p16INK4a 53 100 60
Intense nuclear p16INK4a staining 75 100 85