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Table 2 HPV status and clinico-pathological parameters

From: The role of histologic subtype, p16INK4a expression, and presence of human papillomavirus DNA in penile squamous cell carcinoma

  HR-HPV- HR-HPV+ p-value*
Histopathologic subtype    
keratinizing 38 15  
basaloid 3 2 0.62
Grading    
Low-grade (G1-2) 32 11  
High-grade (G3-4) 9 6 0.33
Presence of tumour invasion    
Non-invasive 5 7  
Invasive 36 10 0.028
Presence of metastasis    
N0M0 10 5  
N+ and/or M+ 11 2 0.40
p16 INK4a immunostaining    
negative 24 0  
scattered 10 0  
intense nuclear/confluent 7 17 <0.001
  1. *Fisher’s exact Test.