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Table 1 Clinico-pathologic sample characteristics

From: The role of histologic subtype, p16INK4a expression, and presence of human papillomavirus DNA in penile squamous cell carcinoma

No. of patients

58

No. of samples

58

Age (mean; range)

64.5; 31-93 years

Tumour characteristics

   

Differentiation

 

Distant metastasis

 

keratinizing

53

Mx

21

basaloid

5

cM0

33

Grading

 

pM+

4

Low-grade (G1-2)

43

  

High-grade (G3-4)

15

p16 INK4a IHC

 

pT stage

 

negative

24

pTis

10

positive

34

pTa

2

intense confluent

24

pT1

19

focally scattered

10

pT2

20

  

pT3

5

  

pT4

2

HPV subtyping

 

Nodal involvement

 

HPV-

40

Nx

30

HPV+

18

pN0

15

HPV-16

16

pN+

13

HPV-45

1

  

HPV-6

1

  1. pTis, carcinoma in situ; pTa, papillary/exophytic (noninvasive) carcinoma; pT1-pT4, depth of tumor invasion; Nx, lymph node status unknown; pN0, (verified) absence of lymph node metastases; pN+, (verified) presence of lymph node metastases; Mx, presence of distant metastases unknown; cM0, no clinical evidence for distant metastases; pM+, (verified) presence of distant metastases; IHC, immunohistochemistry; HPV, human papillomavirus.
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BMC Cancer

ISSN: 1471-2407

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