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Figure 3 | BMC Cancer

Figure 3

From: Identification of sample-specific regulations using integrative network level analysis

Figure 3

Unsupervised hierarchical clustering of breast cancer. Heatmap shows the relative gene expression compared to the median value of normal breast tissue samples of 119 differentially expressed genes. In the IHC color bar, breast cancer samples (columns) are grouped into TNBC, Luminal 1, Luminal 2 and Non-luminal HER2+ based on immunohistochemistry (IHC). In the PAM50 color bar, breast cancer samples are grouped into Basal-like, HER2-enriched, Luminal A, Luminal B and Normal-like based on gene expression. In the heatmap plot, we used euclidean distance measurement and Ward agglomeration method, and heatmap was scaled by row.

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