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Table 7 Correlation between the expression of TLR3 signaling-pathway proteins with those of Ki67, cyclin D1, MMP-2, CD34 and analysis of EPCs in HCC tissues

From: TLR3 expression correlates with apoptosis, proliferation and angiogenesis in hepatocellular carcinoma and predicts prognosis

Item N TLR3 Spearman TRIF Spearman IRF3 Spearman NF-κB Spearman
expression analysis expression analysis expression analysis expression analysis
+ ++ γ P + ++ γ P + ++ γ P + ++ γ P
Ki-67      −0.276 0.011     −0.215 0.048     −0.281 0.009     −0.265 0.014
33 12 4 17    8 9 16    10 12 11    9 12 12   
+ 36 12 15 19    12 7 17    19 9 8    12 14 10   
++ 16 11 3 2    6 9 1    11 3 2    10 5 1   
CyclinD1      −0.269 0.013     −0.219 0.044     −0.292 0.007     −0.262 0.016
36 11 7 18    10 6 20    11 13 12    12 11 13   
+ 28 12 10 6    9 11 8    17 5 6    11 12 5   
++ 21 12 5 4    7 8 6    12 6 3    8 8 5   
MMP-2      −0.378 0.000     −0.294 0.006     −0.196 0.073     −0.248 0.022
37 10 9 18    8 8 21    15 9 13    11 12 14   
+ 25 9 8 8    9 7 9    10 12 3    8 10 7   
++ 23 16 5 2    9 10 4    15 3 5    12 9 2   
MVD      −0.583 0.000     −0.560 0.000     −0.527 0.000     −0.484 0.000
≤120 23 3 4 16    1 4 18    16 7 2    2 8 13   
121–240 37 11 17 9    9 14 14    15 9 13    12 19 6   
>240 25 21 1 3    16 7 2    22 2 1    17 4 4   
EPCs count      −0.544 0.000     −0.458 0.000     −0.277 0.010     −0.345 0.001
≤5 54 13 18 23    10 14 30    21 17 16    14 23 17   
6 - 10 22 14 4 4    8 11 3    10 7 5    10 7 5   
>10 9 8 0 1    8 0 1    9 0 0    7 1 1