Table 1 Main clinical data in overall EC population and in EC patients categorized according to rs4430794 genotypes

191

57

134

Age ¹

64.3 ± 10.6

64.9 ± 10.1

64.0 ± 10.8

Histological type

Type I

162

46 (28.4)

116 (71.6)

Type II ²

29

11 (37.9)

18 (62.1)

0.304

Figo stage ²

I

152

45 (29.6)

107 (70.4)

II

12

4 (33.3)

8 (66.7)

III

23

6 (26.1)

17 (73.9)

IV

4

2 (50.0)

2 (50.0)

0.820

Grading (for Type I)

G1

70

17 (24.3)

53 (75.7)

G2

63

18 (28.6)

45 (71.4)

G3

29

11 (37.9)

18 (62.1)

0.186

Myometrial invasion

<50%

100

30 (30.0)

70 (70.0)

>50%

91

27 (29.7)

64 (70.3)

0.960

Lymph node metastasis (129 lymphadenectomy)

No

113

34 (30.1)

79 (69.9)

Yes

16

4 (25.0)

12 (75.0)

0.677

Adjuvant treatment

None

119

36 (27.9)

83 (64.3)

Radiotherapy

42

12 (28.6)

30 (71.4)

Chemo-Radiotherapy

30

9 (30.0)

21 (70.0)

0.926

Radiotherapy (42 patients)

External beam therapy

2

1 (50.0)

1 (50.0)

Brachytherapy

21

6 (28.6)

15 (71.4)

Combined

19

5 (26.3)

14 (73.7)

0.615