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Figure 4 | BMC Cancer

Figure 4

From: Direct confirmation of quiescence of CD34+CD38- leukemia stem cell populations using single cell culture, their molecular signature and clinicopathological implications

Figure 4

The change of mtDNA copy number in each cell population from total bone marrow cells of AML. Significant reduction of mtDNA copy number was observed in ASCs and CD19+ cell populations compared with other cells. There was statistical differences in mtDNA copy numbers from AML cells (CD33+ cells and CD38+ cells) and ASCs (CD34+CD38- cell) (p < 0.05), but the mtDNA copy number of ASCs was similar to those of normal control cells (CD19+). ASCs showed a lower mtDNA copy number than did non-ASCs (CD34+CD38+ cells), which was not statistically significant (p = 0.0769). Statistical significances were indicated as follows: *, p-value <0.05; and **, p-value <0.01.

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