Figure 4
From: NPC1L1 knockout protects against colitis-associated tumorigenesis in mice
Proteins (p53, β-catenin, TGF-β and p-gp) associated with tumorigenesis were assayed by western blot.(A, B) Protein β-catenin and p53 of adjacent colons and tumors were assayed by western blot. Relative quantities of β-catenin and p53 were analyzed and normalized to actin, respectively. (C, D) TGF-β and p-gp of adjacent colons and tumors were assayed by western blot. Relative quantities of TGF-β and p-gp were analyzed and normalized to α-tubulin, respectively. *p < 0.05, **p < 0.01, #p >0.05, ##p =0.08.