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Table 2 The assessment of the risk of bias in each Cohort study using the Newcastle-Ottawa scale

From: Meta-analysis of the prognostic value of circulating tumor cells detected with the CellSearch System in colorectal cancer

Study Selection (0-4) Comparability(0-2) Outcome (0-3) Total
REC SNEC AE DO SC AF AO FU AFU
Sotelo 2014 [24] * * * * - - * * - 6
Seeberg 2014 [25] * * * * - - * * * 7
Gazzaniga 2013 [26] - * * * - - * - - 4
Aggarwal 2013 [27] - * * * - - * * - 5
Kuboki 2013 [14] - * * * - - * * - 5
Deneve 2013 [13] - * * * - - * * - 5
Sastre 2012 [28] * * * * - - * * - 6
Sato 2012 [29] * * * * - - * - - 5
Papavasiliou 2010 [30] - - * * - - * - - 3
Tol 2010 [31] * * * * - - * - - 5
Hiraiwa 2008 [15] - * * * - - * - - 4
  1. NOTE. REC: representativeness of the exposed cohort; SNEC: selection of the non-exposed cohort; AE: ascertainment of exposure; DO: demonstration that outcome of interest was not present at start of study; SC: study controls for age, sex; AF: study controls for any additional factors (chemoradiotherapy, curative resection); AO: assessment of outcome; FU: follow-up long enough (36M) for outcomes to occur; AFU: adequacy of follow-up of cohorts (≥90%).'*' means that the study is satisfied the item (high quality with no bias), and '-' means that the study is not satisfied the item (low quality with bias); Total: the number of high-quality items (no bias) in each study.