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Table 1 Association between miR-372 expression according to in situ hybridization and conventional clinicopathological parameters in 120 patients with HCC

From: Low mir-372 expression correlates with poor prognosis and tumor metastasis in hepatocellular carcinoma

Characteristics Number of patients Mir-372 Lowexpression Mir-372 Highexpression P
Total cases 120 87 33  
Age (years)     
 ≥50 74 54(72.9%) 20(27.1%) 0.883
 <50 46 33(71.7%) 13(28.3%)
Gender     
 Male 51 37(72.5%) 14(27.5%) 0.992
 Female 69 50(72.4%) 19(27.6%)
Tumor size     
 ≥5 cm 51 33(64.7%) 18(35.3%) 0.100
 <5 cm 69 54(78.3%) 15(21.7%)
Metastasis     
 Yes 37 32(86.5%) 5(13.5%) 0.022
 No 83 55(66.3%) 28(33.7%)
HBsAg status     
 Positive 72 54(75%) 18(25%) 0.453
 Negative 48 33(68.8%) 15(31.3%)
Tumor differentiation     
 High 43 29 (67.4%) 14(32.6%) 0.411
 Moderate 44 35(79.5%) 9(20.5%)
 Poor 33 23(69.7%) 10(30.3%)
Cirrhosis     
 Yes 73 49(67.1%) 24(32.9%) 0.101
 No 47 38(80.9%) 9(19.1%)
Serum AFP     
 <200 ng/dl 68 53(77.9%) 15(22.1%) 0.127
 ≥200 ng/dl 52 34(65.4%) 18(34.6%)
Recurrence*     
 Yes 34 23(67.6%) 11(32.4%) 0.454
 No 86 64(74.4%) 22(25.6%)
Tumor stage     
 I 18 11(61.1%) 7(38.9%) <0.001
 II 32 14(43.8%) 18(56.2%)
 III 40 36(90%) 4(10%)
 IV 30 26(86.7%) 4(13.3%)
  1. Notes: Bold fonts indicate Statistically significant. Recurrence*:follow-up time for five years after therapeutic surgery.