Table 1 Clinicopathologic characteristics of patients according to age
From: Luminal B subtype: A key factor for the worse prognosis of young breast cancer patients in China
Age | <40y | 40 ~ 50y | P value | ||
|---|---|---|---|---|---|
character | No. | % | No. | % | |
T stage | <0.01 | ||||
T1 | 520 | 38.2 | 1072 | 34.5 | |
T2 | 625 | 46.0 | 1914 | 56.3 | |
T3 | 215 | 15.8 | 124 | 9.2 | |
N stage | 0.07 | ||||
N0 | 626 | 46.0 | 1580 | 50.8 | |
N1 | 324 | 23.8 | 787 | 25.3 | |
N2 | 324 | 23.8 | 606 | 19.5 | |
N3 | 86 | 6.4 | 137 | 4.4 | |
Family history | <0.01 | ||||
Yes | 80 | 5.9 | 44 | 1.4 | |
No | 1280 | 94.1 | 3066 | 98.6 | |
Tumor Grade | <0.01 | ||||
Grade I | 56 | 4.1 | 93 | 3.0 | |
Grade II | 775 | 57 | 2233 | 71.8 | |
Grade III | 529 | 38.9 | 784 | 25.2 | |
Tumor type | 0.4 | ||||
IDC | 1216 | 89.4 | 2762 | 88.8 | |
ILC | 60 | 4.4 | 168 | 5.4 | |
Others | 84 | 6.2 | 180 | 5.8 | |
LVI | <0.01 | ||||
Positive | 413 | 30.4 | 790 | 25.4 | |
Negative | 947 | 69.6 | 2320 | 74.6 | |
ER status | <0.01 | ||||
Positive | 821 | 60.4 | 2133 | 68.6 | |
Negative | 539 | 39.6 | 977 | 31.4 | |
PR status | 0.9 | ||||
Positive | 826 | 60.7 | 1894 | 60.9 | |
Negative | 534 | 39.3 | 1216 | 39.1 | |
HER2 status | 0.01 | ||||
Positive | 390 | 28.7 | 647 | 20.8 | |
Negative | 970 | 71.3 | 2463 | 79.2 | |
Subtype | <0.01 | ||||
Luminal A | 660 | 48.5 | 1959 | 59.2 | |
Luminal B | 344 | 25.3 | 579 | 17.5 | |
Her2 positive | 129 | 9.5 | 327 | 9.9 | |
Triple negative | 227 | 16.7 | 445 | 13.4 | |
Srugery | <0.01 | ||||
BCS | 223 | 16.4 | 236 | 7.6 | |
Mastectomy | 1137 | 83.6 | 2874 | 92.4 | |
Endocrine therapy | 0.7 | ||||
No | 204 | 15.0 | 442 | 14.2 | |
Yes | 1156 | 85 | 2668 | 85.8 | |
Chemotherapy | 0.4 | ||||
No | 92 | 6.8 | 308 | 9.9 | |
Yes | 1268 | 93.2 | 2802 | 90.1 | |
Radiotherapy | 0.1 | ||||
No | 1020 | 75.0 | 2568 | 82.6 | |
Yes | 340 | 25.0 | 542 | 17.4 | |