From: Treatment and survival of non-alcoholic steatohepatitis associated hepatocellular carcinoma
Characteristics | NASH - HCC | Non-NASH - HCC | P |
---|---|---|---|
(n = 45) | (n = 1074) | ||
Male gender* | 35 (77.8) | 888 (82.7) | 0.820 |
Age at time of diagnosis# | 67.6 (46.6-89.9) | 65 (15.3-87.3) | 0.007 |
Caucasian* | 45 (100) | 1055 (98.2) | 1,000 |
Obesity* | 13 (28.9) | 158 (14.7) | 0.046 |
BMI (kg/m2)# | 29 (19.4-49.6) | 26.6 (16.5-48.4) | 0.022 |
Type II diabetes * | 30 (66.7) | 406 (37.8) | 0.024 |
Hypertension* | 32 (71.1) | 485 (45.2) | 0.060 |
Hyperlipidemia* | 18 (40) | 211 (19.6) | 0.016 |
Myocardial infarction* | 6 (13.3) | 52 (4.8) | 0.035 |
apoplectic stroke* | 4 (8.9) | 23 (2.1) | 0.025 |
Cirrhosis* | 35 (77.8) | 858 (79.9) | 1,000 |
Child-Turcotte-Pugh-Score* | |||
A | 21 (46.7) | 421 (39.2) | 0.577 |
B | 14 (31.1) | 301 (28) | 0.748 |
C | 0 | 136 (12.7) | 0.012 |
Bilirubin# | 0.8 (0.3-4.8) | 1.2 (0.2-78.3) | <0.001 |
INR# | 1.1 (0.8-1.4) | 1.1 (0.9-3.2) | <0.001 |
Creatinine# | 1 (0.6-7.5) | 0.9 (0.3-7.2) | 0.420 |
Albumin# | 35 (19–52.6) | 34 (3–55.6) | 0.173 |
Thrombocytopenia* | 15 (33.3) | 472 (43.9) | 0.394 |
AFP# | 96.9 (1.5-96611) | 39 (0–624094.4) | 0.722 |
MELD score# | 9 (6–21) | 10 (6–40) | 0.005 |
Encephalopathy* | 0 | 44 (4,1) | 1.640 |
Ascites* | 14 (31.1) | 235 (21.9) | 0.299 |
Varices* | 10 (22.2) | 342 (31.8) | 0.420 |
Portal vein thrombosis* | 13 (28.9) | 222 (20.7) | 0.290 |