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Table 1 Demographic data, prevalence of metabolic risk factors, complications and characteristics of liver function at time of initial HCC diagnosis

From: Treatment and survival of non-alcoholic steatohepatitis associated hepatocellular carcinoma

Characteristics NASH - HCC Non-NASH - HCC P
(n = 45) (n = 1074)
Male gender* 35 (77.8) 888 (82.7) 0.820
Age at time of diagnosis# 67.6 (46.6-89.9) 65 (15.3-87.3) 0.007
Caucasian* 45 (100) 1055 (98.2) 1,000
Obesity* 13 (28.9) 158 (14.7) 0.046
BMI (kg/m2)# 29 (19.4-49.6) 26.6 (16.5-48.4) 0.022
Type II diabetes * 30 (66.7) 406 (37.8) 0.024
Hypertension* 32 (71.1) 485 (45.2) 0.060
Hyperlipidemia* 18 (40) 211 (19.6) 0.016
Myocardial infarction* 6 (13.3) 52 (4.8) 0.035
apoplectic stroke* 4 (8.9) 23 (2.1) 0.025
Cirrhosis* 35 (77.8) 858 (79.9) 1,000
Child-Turcotte-Pugh-Score*    
 A 21 (46.7) 421 (39.2) 0.577
 B 14 (31.1) 301 (28) 0.748
 C 0 136 (12.7) 0.012
Bilirubin# 0.8 (0.3-4.8) 1.2 (0.2-78.3) <0.001
INR# 1.1 (0.8-1.4) 1.1 (0.9-3.2) <0.001
Creatinine# 1 (0.6-7.5) 0.9 (0.3-7.2) 0.420
Albumin# 35 (19–52.6) 34 (3–55.6) 0.173
Thrombocytopenia* 15 (33.3) 472 (43.9) 0.394
AFP# 96.9 (1.5-96611) 39 (0–624094.4) 0.722
MELD score# 9 (6–21) 10 (6–40) 0.005
Encephalopathy* 0 44 (4,1) 1.640
Ascites* 14 (31.1) 235 (21.9) 0.299
Varices* 10 (22.2) 342 (31.8) 0.420
Portal vein thrombosis* 13 (28.9) 222 (20.7) 0.290
  1. *Data presented in (n [%]); #Data presented in (median [range]); Bilirubin (normal range <1 mg/dL), Albumin (normal range 34–48 g/l, platelets count (normal range 150-450/nL), AFP (normal range <8 ng/mL). A p value p<0.05 was considered significant and is marked in bold.