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Table 1 Demographic data, prevalence of metabolic risk factors, complications and characteristics of liver function at time of initial HCC diagnosis

From: Treatment and survival of non-alcoholic steatohepatitis associated hepatocellular carcinoma

Characteristics

NASH - HCC

Non-NASH - HCC

P

(n = 45)

(n = 1074)

Male gender*

35 (77.8)

888 (82.7)

0.820

Age at time of diagnosis#

67.6 (46.6-89.9)

65 (15.3-87.3)

0.007

Caucasian*

45 (100)

1055 (98.2)

1,000

Obesity*

13 (28.9)

158 (14.7)

0.046

BMI (kg/m2)#

29 (19.4-49.6)

26.6 (16.5-48.4)

0.022

Type II diabetes *

30 (66.7)

406 (37.8)

0.024

Hypertension*

32 (71.1)

485 (45.2)

0.060

Hyperlipidemia*

18 (40)

211 (19.6)

0.016

Myocardial infarction*

6 (13.3)

52 (4.8)

0.035

apoplectic stroke*

4 (8.9)

23 (2.1)

0.025

Cirrhosis*

35 (77.8)

858 (79.9)

1,000

Child-Turcotte-Pugh-Score*

   

 A

21 (46.7)

421 (39.2)

0.577

 B

14 (31.1)

301 (28)

0.748

 C

0

136 (12.7)

0.012

Bilirubin#

0.8 (0.3-4.8)

1.2 (0.2-78.3)

<0.001

INR#

1.1 (0.8-1.4)

1.1 (0.9-3.2)

<0.001

Creatinine#

1 (0.6-7.5)

0.9 (0.3-7.2)

0.420

Albumin#

35 (19–52.6)

34 (3–55.6)

0.173

Thrombocytopenia*

15 (33.3)

472 (43.9)

0.394

AFP#

96.9 (1.5-96611)

39 (0–624094.4)

0.722

MELD score#

9 (6–21)

10 (6–40)

0.005

Encephalopathy*

0

44 (4,1)

1.640

Ascites*

14 (31.1)

235 (21.9)

0.299

Varices*

10 (22.2)

342 (31.8)

0.420

Portal vein thrombosis*

13 (28.9)

222 (20.7)

0.290

  1. *Data presented in (n [%]); #Data presented in (median [range]); Bilirubin (normal range <1 mg/dL), Albumin (normal range 34–48 g/l, platelets count (normal range 150-450/nL), AFP (normal range <8 ng/mL). A p value p<0.05 was considered significant and is marked in bold.