Prognostic significance of interim PET/CT based on visual, SUV-based, and MTV-based assessment in the treatment of peripheral T-cell lymphoma

Table 2 Receiver operating characteristic (ROC) values for predicting disease progression

Assessment parameter	Sn (%)	Sp (%)	PPV (%)	NPV (%)	Area under ROC curves	95% CI	Pvalue
Visual assessment (Grade ≥ 3)	69.4	65.2	87.8	96.1	0.731	0.597-0.864	0.003
ΔSUVmax cutoff	81.8	58.3	92.3	90.0	0.673	0.626-0.874	0.002
ΔMTV2.5 cutoff	77.3	61.1	92.8	93.5	0.627	0.590-0.852	0.005

Abbreviations: Sn, sensitivity; Sp, specificity; PPV, positive predictive value, NPV, negative predictive value, ΔSUVmax, reduction rate of the maximal standardized uptake value; ΔMTV2.5, reduction rate of metabolic tumor volume.

ISSN: 1471-2407