Figure 3

DNA copy number and RNA expression data from patient #160. Copy number plot with the x-axis denoting each point across the genome - each chromosome is highlighted in a different colour starting with chromosome 1 on the left side. Y-axis enumerates the log-2 copy number value at each point across the genome. Red arrows indicate gene amplifications highlighted in this manuscript and corresponding RNASeq expression readouts are displayed in blue boxes. Normal E2F3 copy number in primary tumour (log₂ copy number ratio 0.07) and amplification of E2F3 in the metastasis (log₂ copy number ratio 1.17). Normal CDK4 copy number in primary tumour (log₂ copy number ratio 0.20) and amplification of CDK4 in the metastasis (log₂ copy number ratio 1.53). Normal AKT1 copy number in primary tumour (log₂ copy number ratio 0.16) and amplification of AKT1 in the metastasis (log₂ copy number ratio 1.12).