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Table 4 Stage-specific three-year relative survival of patients with extrapulmonary small cell carcinoma diagnosed in SEER-13 according to site, 1992-2010*

From: A population-based study of incidence and patient survival of small cell carcinoma in the United States, 1992–2010

  No. RS (%) (95%CI) RSR (95%CI)
Limited stage
 Uterine cervix 164 51.6 (43.3, 59.2) 1.00  
 Salivary glands 27 67.7 (41.9, 83.9) 1.31 (0.93, 1.86)
 Esophagus 56 33.2 (20.6, 46.3) 0.64 (0.42, 0.98)
 Stomach 18 ~   ~  
 Colon/rectum 59 40.0 (26.5, 53.2) 0.78 (0.53, 1.13)
 Pancreas 15 ~   ~  
 Larynx 31 34.0 (17.7, 51.0) 0.66 (0.39, 1.12)
 Female breast 39 62.5 (42.3, 77.3) 1.21 (0.88, 1.68)
 Ovary 33 41.0 (23.9, 57.4) 0.79 (0.51, 1.24)
 Prostate 50 36.4 (21.5, 51.4) 0.71 (0.45, 1.10)
 Urinary bladder 256 40.5 (33.6, 47.4) 0.78 (0.62, 0.99)
Distant stage
 Uterine cervix 74 9.4 (3.8, 18.0) 1.00  
 Salivary glands 12 ~   ~  
 Esophagus 75 1.4 (0.1, 6.7) 0.15 (0.02, 1.22)
 Stomach 42 5.1 (0.9, 15.2) 0.54 (0.12, 2.56)
 Colon/rectum 116 2.2 (0.4, 6.6) 0.23 (0.05, 1.10)
 Pancreas 118 1.8 (0.3, 5.8) 0.19 (0.04, 0.96)†
 Larynx 2 ~   ~  
 Female breast 14 ~   ~  
 Ovary 65 19.9 (10.8, 31.0) 2.12 (0.83, 5.37)
 Prostate 88 7.4 (2.9, 14.9) 0.79 (0.26, 2.43)
 Urinary bladder 87 2.9 (0.6, 9.0) 0.31 (0.07, 1.46)
  1. Abbreviations: CI confidence interval, No. number, RS relative survival, RSR RS ratio, SEER-13 13 cancer registry areas of the Surveillance, Epidemiology and End Results Program, ~ relative survival not calculated for < 25 cases.
  2. *Based on microscopically confirmed cases of small cell carcinoma diagnosed during 1992–2010 and followed through 2011. To allow a general overview of stage across primary sites, we used the SEER historic stage variable that includes localized (confined to the organ of origin), regional (direct extension to adjacent organ/tissue or regional lymph nodes), distant (discontinuous metastases), and unspecified stages. We combined localized and regional stages into the category of “limited” stage and maintained the distant stage variable as defined in the SEER Program.
  3. 95 % CI excludes 1.00 (based on unrounded upper and lower CI), and RSR is significant (P < 0.05).