A population-based study of incidence and patient survival of small cell carcinoma in the United States, 1992–2010

Table 4 Stage-specific three-year relative survival of patients with extrapulmonary small cell carcinoma diagnosed in SEER-13 according to site, 1992-2010*

	No.	RS (%)	(95%CI)	RSR	(95%CI)
Limited stage
Uterine cervix	164	51.6	(43.3, 59.2)	1.00
Salivary glands	27	67.7	(41.9, 83.9)	1.31	(0.93, 1.86)
Esophagus	56	33.2	(20.6, 46.3)	0.64	(0.42, 0.98)^†
Stomach	18	~		~
Colon/rectum	59	40.0	(26.5, 53.2)	0.78	(0.53, 1.13)
Pancreas	15	~		~
Larynx	31	34.0	(17.7, 51.0)	0.66	(0.39, 1.12)
Female breast	39	62.5	(42.3, 77.3)	1.21	(0.88, 1.68)
Ovary	33	41.0	(23.9, 57.4)	0.79	(0.51, 1.24)
Prostate	50	36.4	(21.5, 51.4)	0.71	(0.45, 1.10)
Urinary bladder	256	40.5	(33.6, 47.4)	0.78	(0.62, 0.99)^†
Distant stage
Uterine cervix	74	9.4	(3.8, 18.0)	1.00
Salivary glands	12	~		~
Esophagus	75	1.4	(0.1, 6.7)	0.15	(0.02, 1.22)
Stomach	42	5.1	(0.9, 15.2)	0.54	(0.12, 2.56)
Colon/rectum	116	2.2	(0.4, 6.6)	0.23	(0.05, 1.10)
Pancreas	118	1.8	(0.3, 5.8)	0.19	(0.04, 0.96)†
Larynx	2	~		~
Female breast	14	~		~
Ovary	65	19.9	(10.8, 31.0)	2.12	(0.83, 5.37)
Prostate	88	7.4	(2.9, 14.9)	0.79	(0.26, 2.43)
Urinary bladder	87	2.9	(0.6, 9.0)	0.31	(0.07, 1.46)

Abbreviations: CI confidence interval, No. number, RS relative survival, RSR RS ratio, SEER-13 13 cancer registry areas of the Surveillance, Epidemiology and End Results Program, ~ relative survival not calculated for < 25 cases.
*Based on microscopically confirmed cases of small cell carcinoma diagnosed during 1992–2010 and followed through 2011. To allow a general overview of stage across primary sites, we used the SEER historic stage variable that includes localized (confined to the organ of origin), regional (direct extension to adjacent organ/tissue or regional lymph nodes), distant (discontinuous metastases), and unspecified stages. We combined localized and regional stages into the category of “limited” stage and maintained the distant stage variable as defined in the SEER Program.
^†95 % CI excludes 1.00 (based on unrounded upper and lower CI), and RSR is significant (P < 0.05).

ISSN: 1471-2407