Table 3 Stage-specific three-year relative survival of patients with small cell lung carcinoma and extrapulmonary small cell carcinoma diagnosed in SEER-13 according to gender, age, and calendar year, 1992-2010*
SCLC | EPSCC | EPSCC-to-SCLC | ||||||
|---|---|---|---|---|---|---|---|---|
Stage | No. | RS (%) | (95%CI) | No. | RS (%) | (95%CI) | RSR | (95%CI) |
Total † | ||||||||
Limited | 12,070 | 20.7 | (19.9, 21.5) | 907 | 42.7 | (39.1, 46.2) | 2.06 | (1.88, 2.26)‡ |
Distant | 29,003 | 4.0 | (3.7, 4.2) | 835 | 6.2 | (4.6, 8.1) | 1.55 | (1.16, 2.07)‡ |
Gender and age | ||||||||
Males, <60 years | ||||||||
Limited | 1,407 | 24.9 | (22.6, 27.3) | 124 | 37.0 | (28.2, 45.7) | 1.49 | (1.15, 1.92)‡ |
Distant | 3,993 | 4.8 | (4.2, 5.5) | 121 | 7.8 | (3.8, 13.6) | 1.63 | (0.85, 3.11) |
Females, <60 years | ||||||||
Limited | 1,442 | 31.2 | (28.7, 33.7) | 251 | 51.8 | (45.2, 58.1) | 1.66 | (1.43, 1.93)‡ |
Distant | 3,043 | 7.2 | (6.2, 8.1) | 169 | 11.1 | (6.7, 16.8) | 1.54 | (0.96, 2.49) |
Males, ≥60 years | ||||||||
Limited | 4,469 | 16.8 | (15.6, 18.0) | 312 | 40.3 | (34.0, 46.6) | 2.40 | (2.02, 2.85)‡ |
Distant | 11,594 | 2.8 | (2.5, 3.1) | 297 | 3.7 | (1.8, 6.7) | 1.32 | (0.69, 2.53) |
Females, ≥60 years | ||||||||
Limited | 4,752 | 19.7 | (18.5, 21.0) | 220 | 38.8 | (31.6, 45.9) | 1.97 | (1.62, 2.40)‡ |
Distant | 10,373 | 4.0 | (3.6, 4.4) | 248 | 4.9 | (2.6, 8.4) | 1.23 | (0.67, 2.25) |
Race and age | ||||||||
Whites, <60 years | ||||||||
Limited | 2,360 | 28.9 | (27.1, 30.8) | 282 | 47.0 | (40.8, 52.9) | 1.63 | (1.41, 1.88)‡ |
Distant | 5,849 | 5.7 | (5.1, 6.4) | 224 | 10.1 | (6.5, 14.7) | 1.77 | (1.16, 2.70)‡ |
Blacks, <60 years | ||||||||
Limited | 327 | 21.3 | (16.9, 26.1) | 44 | 25.1 | (13.3, 38.9) | 1.18 | (0.67, 2.08) |
Distant | 796 | 5.1 | (3.7, 6.9) | 36 | 10.7 | (3.2, 23.5) | 2.10 | (0.76, 5.81) |
Whites, ≥60 years | ||||||||
Limited | 7,887 | 18.5 | (17.6, 19.4) | 449 | 38.7 | (33.4, 43.8) | 2.09 | (1.81, 2.42)‡ |
Distant | 18,793 | 3.3 | (3.0, 3.6) | 451 | 4.5 | (2.7, 7.0) | 1.36 | (0.84, 2.21) |
Blacks, ≥60 years | ||||||||
Limited | 699 | 16.5 | (13.6, 19.6) | 41 | 47.5 | (30.6, 62.6) | 2.88 | (1.95, 4.25)‡ |
Distant | 1,770 | 3.2 | (2.4, 4.2) | 50 | 4.3 | (0.8, 13.1) | 1.34 | (0.33, 5.46) |
Primary tumor size | ||||||||
≤3 cm | ||||||||
Limited | 2,930 | 29.2 | (27.5, 31.0) | 187 | 57.1 | (48.8, 64.6) | 1.96 | (1.68, 2.27)‡ |
Distant | 4,469 | 5.5 | (4.8, 6.2) | 67 | 11.3 | (4.7, 20.9) | 2.05 | (0.98, 4.32) |
>3 cm - ≤7 cm | ||||||||
Limited | 3,391 | 21.6 | (20.1, 23.1) | 255 | 38.9 | (32.3, 45.3) | 1.80 | (1.50, 2.16)‡ |
Distant | 6,817 | 4.2 | (3.7, 4.7) | 210 | 3.7 | (1.6, 7.0) | 0.88 | (0.41, 1.87) |
>7 cm | ||||||||
Limited | 1,071 | 15.6 | (13.3, 18.0) | 117 | 37.0 | (27.8, 46.3) | 2.37 | (1.76, 3.19)‡ |
Distant | 3,079 | 4.9 | (4.1, 5.7) | 135 | 12.6 | (7.3, 19.5) | 2.57 | (1.55, 4.27)‡ |
Year of diagnosis | ||||||||
1992-2000 | ||||||||
Limited | 6,660 | 18.9 | (17.9, 19.9) | 364 | 40.9 | (35.5, 46.3) | 2.16 | (1.87, 2.50)‡ |
Distant | 14,006 | 3.5 | (3.2, 3.8) | 314 | 5.5 | (3.2, 8.5) | 1.57 | (0.98, 2.53) |
2001-2010 | ||||||||
Limited | 5,410 | 23.0 | (21.7, 24.2) | 543 | 43.8 | (39.1, 48.4) | 1.90 | (1.69, 2.14)‡ |
Distant | 14,997 | 4.4 | (4.1, 4.8) | 521 | 6.7 | (4.6, 9.3) | 1.52 | (1.06, 2.19)‡ |