Table 3 Dot blot analysis of tyrosine receptor kinase phosphorylation in SW1736, HTh7, BHT101 and ML1 cells after short-term (10 min) treatment with 3 μM sorafenib

p-VEGFR1

41.3 ± 7.2*

27.2 ± 11.5*

62.5 ± 7.4*

70.3 ± 4.6*

p-VEGFR2

30.3 ± 10.2*

45.7 ± 8.8*

60.7 ± 5.7*

75.6 ± 6.7*

p-VEGFR3

44.2 ± 7.2*

67.9 ± 8.9*

68.3 ± 10.4*

94.1 ± 7.1

p-PDGFRA

46.6 ± 6.0*

28.5 ± 11.1*

n.e.

n.e.

p-PDGFRB

67.0 ± 8.1*

57.3 ± 6.8*

67.2 ± 10.9*

64.2 ± 9.0*

p-EGFR

102.8 ± 7.8

107.4 ± 10.4

105.0 ± 7.3

93.0 ± 11.4

p-ERBB2

96.3 ± 6.9

91.8 ± 9.9

101.5 ± 11.8

101.9 ± 9.3

p-ERBB3

111.3 ± 8.8

108.7 ± 7.4

95.3 ± 10.8

96.2 ± 11.6

p-ERBB4

107.5 ± 11.0

110.3 ± 12.4

94.9 ± 10.71

102.6 ± 7.8

p-insulinR

103.9 ± 6.9

97.7 ± 10.3

96.6 ± 8.8

112.1 ± 12.0

p-IGF1R

112.6 ± 10.5

101.8 ± 9.9

95.9 ± 8.9

110.3 ± 10.3