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Figure 1 | BMC Cancer

Figure 1

From: Sorafenib inhibits intracellular signaling pathways and induces cell cycle arrest and cell death in thyroid carcinoma cells irrespective of histological origin or BRAF mutational status

Figure 1

Sorafenib reduced the viability of thyroid carcinoma cell lines of different histological derivation. Cells were cultured with increasing concentrations of sorafenib or vehicle (DMSO) control for 48 h, and viability was assessed by MTT assay. Values are reported as percent of vehicle control ± standard deviation, and represent mean values of eight determinations of one representative experiment of three. IC50 values and the lowest concentration that caused a significant loss of viability for all cell lines examined are depicted in Table 1.

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