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Table 3 Univariable analysis of association with biochemical failure and distant metastasis

From: The role of androgen deprivation therapy on biochemical failure and distant metastasis in intermediate-risk prostate cancer: effects of radiation dose escalation

 

Biochemical failure

Distant metastasis

Variable

Hazard

95% CI

p-value

Hazard

95% CI

p-value

 

Ratio

  

Ratio

  

Age

1.000

0.980-1.02

0.983

1.016

0.968-1.067

0.522

Pre-treatment PSA

1.075

1.045-1.106

<0.001

1.043

0.975-1.115

0.22

Gleason Score

0.863

0.761-0.978

0.021

1.100

0.796-1.519

0.564

Year of Diagnosis

0.902

0.875-0.930

<0.001

0.926

0.858-0.999

0.046

T-stage

1.215

1.043-1.416

0.012

1.668

1.125-2.474

0.011

Radiation Dose (high vs low)

0.431

0.320-0.581

<0.001

0.593

0.287-1.226

0.158

ADT use (yes vs no)

0.422

0.274-0.651

<0.001

0.119

0.016-0.882

0.037

Length of Hormone use

0.981

0.938-1.026

0.403

1.000

0.914-1.094

0.997

Race

0.795

0.611-1.034

0.087

0.678

0.318-1.444

0.263

ADT Timing (Neoadjuvant vs adjuvant)

1.514

0.444-5.160

0.507

1.047

0.408-2.688

0.924