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Table 7 Details of lung cancer patients with TP53 mutations in their tumours

From: Prognostic role of serum p53 antibodies in lung cancer

Patient number Sex Age Histology* TNM G§ p53Abs IHC Exon Codon Nucleic acid change Aminoacid change
8 M 70 SCC IB 3 N& P# 2 12 c.35C > T Pro12Leu
4 M 70 ADC IB 3 P P 2 12 c.35C > T Pro12Leu
54 M 59 ADC IIB 3 N N 4 66-81 c.196_241del46 Frameshift
1 M 72 SCC IA 3 N P 4 110 c.329G > T Arg110Leu
55 M 77 SCC IA 3 N N 5 152 c.456delG Frameshift
10 F 55 SCC IIB 3 N P 5 154 c.460_474del15 Frameshift
2 M 65 LCC IB 3 N P 5 157 c.469G > T Val157Phe
5 M 41 APC IIB 3 P P 5 158 c.473G > T Arg158Leu
3 M 76 SCC IIB 3 N P 5 159 c.475G > C Ala159Pro
7 M 73 SCC IB 2 N P 5 167 c.501G > T Gln167His
11 F 68 ADC IB 2 N P 6 199-200 c.596_598delGAA Frameshift
56 M 70 ADC IA 2 N N 8 269 c.807delC Frameshift
6 F 82 ADC IIB 2 P P 8 273 c.817C > T Arg273Cys
9 M 50 ADC IB 3 N P 8 282 c.844C > T Arg282Trp
12 F 70 SCC IB 2 N P 8 288 c.862delA Frameshift
13 M 79 SCC IIB 3 N P 8 288 c.862delA Frameshift
  1. *SCC, squamous cell carcinoma; ADC, adenocarcinoma; APC, anaplastic carcinoma; LCC, large cell carcinoma. §Grade; &Low/Negative, #Positive.