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Table 3 Top ten significantly up-regulated genes in LNCaP cells after EPHB4 siRNA knockdown

From: The tumour-promoting receptor tyrosine kinase, EphB4, regulates expression of Integrin-β8 in prostate cancer cells

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Gene symbol

Description

Function

5.7

MYO6

Myosin VI

Actin-based motor protein

4.8

MMP12

Matrix-metallopeptidase 12

Cleavage of extra-cellular matrix

4.4

LOC100131726

HCC-related HCC-C11_v3

Miscellaneous RNA

4.3

TDRD7

Tudor Domain containing 7

Component of cytoplasmic RNA granules

4.3

OSMR

Oncostatin M receptor

Type I cytokine receptor

4.3

APOBEC3H

Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H

Antiretroviral mRNA editing enzyme

4.2

CYP11A1

Cytochrome P450, family 11, subfamily A, polypeptide 1

Conversion of cholesterol to pregnolone

4.2

LRRTM3

Leucine Rich Repeat Transmembrane Neuronal 3

Implicated in neuronal disorders

4.1

GCOM1

GRINL1A complex locus 1

Read-through transcription between the MYZAP (myocardial zonula adherens protein) and POLR2M (polymerase (RNA) II (DNA directed) polypeptide M

3.9

TBC1D8B

TBC1 domain family, member 8B

Uncharacterized