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Table 3 Top ten significantly up-regulated genes in LNCaP cells after EPHB4 siRNA knockdown

From: The tumour-promoting receptor tyrosine kinase, EphB4, regulates expression of Integrin-β8 in prostate cancer cells

Fold change Gene symbol Description Function
5.7 MYO6 Myosin VI Actin-based motor protein
4.8 MMP12 Matrix-metallopeptidase 12 Cleavage of extra-cellular matrix
4.4 LOC100131726 HCC-related HCC-C11_v3 Miscellaneous RNA
4.3 TDRD7 Tudor Domain containing 7 Component of cytoplasmic RNA granules
4.3 OSMR Oncostatin M receptor Type I cytokine receptor
4.3 APOBEC3H Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H Antiretroviral mRNA editing enzyme
4.2 CYP11A1 Cytochrome P450, family 11, subfamily A, polypeptide 1 Conversion of cholesterol to pregnolone
4.2 LRRTM3 Leucine Rich Repeat Transmembrane Neuronal 3 Implicated in neuronal disorders
4.1 GCOM1 GRINL1A complex locus 1 Read-through transcription between the MYZAP (myocardial zonula adherens protein) and POLR2M (polymerase (RNA) II (DNA directed) polypeptide M
3.9 TBC1D8B TBC1 domain family, member 8B Uncharacterized