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Table 3 Univariate and multivariate Cox proportional hazard regression analyses of cancer-specific survival

From: Are urothelial carcinomas of the upper urinary tract a distinct entity from urothelial carcinomas of the urinary bladder? Behavior of urothelial carcinoma after radical surgery with respect to anatomical location: a case control study

 

Univariate

Multivariate

 

HR (95% CI)

P value

HR (95% CI)

P value

Tumor location

    

Upper urinary tract vs. Bladder

0.889 (0.650-1.216)

0.462

  

Age, years

1.022 (1.005-1.039)

0.010

1.027 (1.010-1.044)

0.002

Sex

    

Female vs. Male

0.980 (0.643-1.493)

0.926

  

Body mass index, kg/m2

0.921 (0.874-0.971)

0.002

0.965 (0.916-1.016)

0.177

ASA score

    

≥2 vs.1

0.978 (0.711-1.343)

0.889

  

Hydronephrosis

    

Present vs. Absent

1.672 (1.221-2.289)

0.001

1.409 (1.015-1.957)

0.041

Pathological T category

    

pT2 vs. ≤pT1

3.410 (1.919-6.058)

<0.001

2.707 (1.500-4.884)

0.001

≥pT3 vs. ≤pT1

7.115 (4.366-11.593)

<0.001

4.960 (2.943-8.359)

<0.001

Pathological N category

    

pNx vs. pN-

1.126 (0.784-1.619)

0.520

1.126 (0.760-1.669)

0.554

pN+ vs. pN-

3.580 (2.364-5.422)

<0.001

1.986 (1.282-3.074)

0.002

Tumor grade

    

III vs. ≤II

1.963 (1.432-2.689)

<0.001

1.105 (0.778-1.567)

0.578

LVI

    

Present vs. Absent

2.875 (2.098-3.938)

<0.001

1.663 (1.164-2.374)

0.005

Associated CIS

    

Present vs. Absent

0.971 (0.624-1.512)

0.898

  

Surgical margin

    

Positive vs. Negative

3.158 (1.930-5.166)

<0.001

1.483 (0.888-2.477)

0.132

  1. Abbreviations: HR = hazard ratio, CI = confidence interval, ASA = American Society of Anesthesiologists, LVI = Lymphovascular invasion, CIS = carcinoma in situ.