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Table 3 Statistically significant (p < 0.05) correlations between percentage changes (Δ) in pairs of measured volumes (GTV-CT, GTV-MR, GTV-DW, GTV-PET) and functional parameters (SUVmax, mean ADC value (ADC), Plasma Flow (PF), Plasma Volume (PV), Interstitial Volume (νe), Permeability Surface Area Product (PS), Extraction Fraction (EF) and Ktrans)

From: Alterations in anatomic and functional imaging parameters with repeated FDG PET-CT and MRI during radiotherapy for head and neck cancer: a pilot study

Time interval Parameter 1 Parameter 2 Correlation coefficient p-value
Baseline to Fraction 11 ΔGTV-CT ΔGTV-MR 0.820 0.0239
ΔGTV-CT Δνe −0.923 0.0030
ΔGTV-CT ΔPS −0.874 0.0101
ΔGTV-CT ΔEF −0.885 0.0081
ΔGTV-CT ΔKtrans −0.872 0.0105
ΔGTV-CT ΔSUVmax 0.910 0.0044
ΔGTV-MR ΔGTV-DW 0.785 0.0210
ΔGTV-MR Δνe −0.817 0.0134
ΔGTV-MR ΔPS −0.973 0.0001
ΔGTV-MR ΔEF −0.887 0.0033
ΔGTV-MR Δ Ktrans −0.974 0.0000
ΔGTV-DW ΔPS −0.753 0.0311
ΔGTV-DW Δ Ktrans −0.754 0.0306
ΔPF ΔPV 0.969 0.0001
Δνe ΔPS 0.914 0.0015
Δνe ΔEF 0.983 0.0000
Δνe Δ Ktrans 0.909 0.0018
ΔPS ΔEF 0.960 0.0002
ΔPS Δ Ktrans 1.000 0.0000
ΔEF Δ Ktrans 0.955 0.0002
Baseline to Fraction 21 ΔGTV-CT ΔGTV-DW 0.851 0.0316
ΔGTV-CT ΔPF 0.926 0.0237
ΔGTV-MR ΔADC 0.887 0.0185
ΔGTV-MR ΔPS −0.954 0.0118
ΔGTV-MR ΔEF −0.962 0.0088
ΔGTV-MR Δ Ktrans −0.964 0.0019
ΔADC Δ Ktrans −0.847 0.0334
ΔPF Δνe −0.936 0.0191
ΔPF ΔSUVmax 0.934 0.0203
ΔPS ΔEF 0.981 0.0032
ΔPS Δ Ktrans 1.000 0.0000
ΔEF Δ Ktrans 0.981 0.0030
Fraction 11 to Fraction 21 ΔGTV-DW ΔPF 0.899 0.0381
ΔPS ΔEF 0.972 0.0057
ΔPS Δ Ktrans 1.000 0.0000
ΔEF Δ Ktrans 0.967 0.0073