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Table 2 Median [range] and p-value of percentage change in parameters between imaging timepoints (Baseline, Fraction 11 and Fraction 21)

From: Alterations in anatomic and functional imaging parameters with repeated FDG PET-CT and MRI during radiotherapy for head and neck cancer: a pilot study

Parameter Baseline to Fraction 11 Baseline to Fraction 21 Fraction 11 to Fraction 21
GTV-CT −24 [−78,−6] −53 [−82,−27] −23 [−53,−13]
(cm3) p = 0.016 p = 0.016 p = 0.016
GTV-MR −31 [−88,−3] −70 [−92,−61] −58 [−81,−32]
(cm3) p = 0.008 p = 0.031 p = 0.031
GTV-DW −53 [−77,−19] −79 [−93,−63] −62 [−73,−36]
(cm3) p = 0.008 p = 0.031 p = 0.031
GTV-PET −20 [−49,105] −16 [−69,374] 18 [−64,132]
(cm3) p = 0.375 p = 0.297 p = 0.578
SUVmax −26 [−84,−18] −60 [−78,−33] −19 [−47,36]
p = 0.016 p = 0.016 p = 0.219
Mean ADC value 37 [6,64] 48 [−1,105] 16 [−37,41]
(x10−3mm2s−1) p = 0.008 p = 0.063 p = 0.563
Plasma Flow (ml/min/100 ml) 35 [15,205] 62 [35,77] 7 [4,54]
p = 0.008 p = 0.063 p = 0.063
Plasma Volume 36 [18,155] 31 [−32,45] −2 [−53,8]
(ml/100 ml) p = 0.008 p = 0.313 p = 0.625
Interstitial Volume 11 [−47,165] 99 [−6,213] 37 [18,129]
(ml/100 ml) p = 0.461 p = 0.125 p = 0.063
Permeability Surface Area Product (ml/min/100 ml) 12 [−33,240] 290 [1,481] 75 [21,360]
p = 0.313 p = 0.063 p = 0.063
Extraction Fraction (%) −21 [−62,150] 118 [−32,286] 55 [12,290]
p = 0.641 p = 0.313 p = 0.063
Ktrans (min−1) 16 [−28,222] 15 [−100,422] 41 [−100,307]
p = 0.148 p = 0.461 p = 0.742
  1. Statistically significant results indicated in bold type.