Figure 7
In vivo study of TYMP shRNA plus dT-QX treatment in the subcutaneous Bel-7402 mouse tumor model. (a) Growth profile of the tumor size over 2 repeated treatment with or without intratumoral injection of TYMP shRNA followed by intravenous injection of dT-QX or PBS; Statistical analysis of the treatments was performed with GraphPad Prism software using two way ANOVA with Bonferroni posttests, indicating that there was significant difference over time between the group of it-TYMP shRNA + iv dT-QX and other three groups (P < 0.05). (b) Images of the tumors after 2 repeated treatment with intratumoral shRNA injection.