From: A novel engineered VEGF blocker with an excellent pharmacokinetic profile and robust anti-tumor activity
Group
% of CD31 in Colo-205
% of CD31 in A549
PBS
6.2 (+/- 2.1)
7.1 (+/-3.2)
Doxorubicin, 3Â mg/kg
6.8 (+/- 3.6)
not done
HB-002.1, 5Â mg/kg
1.9 (+/- 0.9)
0.7 (+/- 0.2)
Bevacizumab, 20Â mg/kg
3.9 (+/- 2.9)