Figure 2From: Successful control of heavily pretreated metastatic gastric cancer with the mTOR inhibitor everolimus (RAD001) in a patient with PIK3CA mutation and pS6 overexpression Mutation analysis of the PIK3CA gene was performed on gastroscopic biopsy specimen obtained before everolimus re-treatment, revealing one of the classical activating PIK3CA mutations at hotspot E545K in exon 9. Back to article page