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Table 7 Numerical and percentage distribution of VEGFR-1/pVEGFR-1 co-expression in the vasculature

From: Cell type- and tumor zone-specific expression of pVEGFR-1 and its ligands influence colon cancer metastasis

  N0/M0 n (%) N+ n (%) N0/M0 vs. N + p M+ n (%) N0/M0 vs. M + p
VEGFR1+/pVEGFR-1 Tyr1048 +
Capillaries zone 1 22/9 (41) 10/4 (40) NS 1.0 14/7 (50) NS 0.7
  zone 2 28/11 (39) 13/8 (62) NS 0.3 19/13 (68) NS 0.08
  zone 3 21/12 (57) 12/8 (67) NS 0.7 11/5 (45) NS 0.7
small vessels zone 1 23/19 (83) 11/4 (36) 0.01 12/5 (42) 0.02
  zone 2 29/20 (69) 15/12 (80) NS 0.5 17/14 (82) NS 0.5
  zone 3 27/22 (81) 14/13 (93) NS 0.6 13/7 (54) NS 0.2
VEGFR-1+/pVEGFR-1 Tyr1213 +
Capillaries zone 1 21/6 (28) 8/2 (25) NS 1.0 14/2 (14) NS 0.4
  zone 2 27/7 (26) 12/3 (25) NS 1.0 18/1 (6) NS 0.1
  zone 3 27/16 (59) 14/5 (36) NS 0.2 13/7 (54) NS 1.0
small vessels zone 1 22/12 (55) 11/3 (27) NS 0.3 11/2 (18) 0.05
  zone 2 28/13 (46) 16/8 (50) NS 1.0 16/2 (13) 0.04
  zone 3 27/16 (59) 14/5 (36) NS 0.2 13/7 (54) NS 1.0
  1. n: total number of VEGFR-1 positive cases/total number of pVEGFR-1 positive cases with concomitant VEGFR-1 positivity. p < 0.05 statistically significant, NS not significant.