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Table 7 Numerical and percentage distribution of VEGFR-1/pVEGFR-1 co-expression in the vasculature

From: Cell type- and tumor zone-specific expression of pVEGFR-1 and its ligands influence colon cancer metastasis

 

N0/M0 n (%)

N+ n (%)

N0/M0 vs. N + p

M+ n (%)

N0/M0 vs. M + p

VEGFR1+/pVEGFR-1 Tyr1048 +

Capillaries

zone 1

22/9 (41)

10/4 (40)

NS 1.0

14/7 (50)

NS 0.7

 

zone 2

28/11 (39)

13/8 (62)

NS 0.3

19/13 (68)

NS 0.08

 

zone 3

21/12 (57)

12/8 (67)

NS 0.7

11/5 (45)

NS 0.7

small vessels

zone 1

23/19 (83)

11/4 (36)

0.01

12/5 (42)

0.02

 

zone 2

29/20 (69)

15/12 (80)

NS 0.5

17/14 (82)

NS 0.5

 

zone 3

27/22 (81)

14/13 (93)

NS 0.6

13/7 (54)

NS 0.2

VEGFR-1+/pVEGFR-1 Tyr1213 +

Capillaries

zone 1

21/6 (28)

8/2 (25)

NS 1.0

14/2 (14)

NS 0.4

 

zone 2

27/7 (26)

12/3 (25)

NS 1.0

18/1 (6)

NS 0.1

 

zone 3

27/16 (59)

14/5 (36)

NS 0.2

13/7 (54)

NS 1.0

small vessels

zone 1

22/12 (55)

11/3 (27)

NS 0.3

11/2 (18)

0.05

 

zone 2

28/13 (46)

16/8 (50)

NS 1.0

16/2 (13)

0.04

 

zone 3

27/16 (59)

14/5 (36)

NS 0.2

13/7 (54)

NS 1.0

  1. n: total number of VEGFR-1 positive cases/total number of pVEGFR-1 positive cases with concomitant VEGFR-1 positivity. p < 0.05 statistically significant, NS not significant.