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Table 6 Percentage distribution of the VEGFR-1 ligands, VEGFR-1 and pVEGFR-1 in inflammatory cells of CC tissue

From: Cell type- and tumor zone-specific expression of pVEGFR-1 and its ligands influence colon cancer metastasis

  N0/M0 (%) N+ (%) M+ (%)
z1 z2 z1 N0/M0 vs. N + p z2 N0/M0 vs. N + p z1 N0/M0 vs. M + p z2 N0/M0 vs. M + p
VEGF 3 5 5 NS 1.0 18 NS 0.2 5 NS 1.0 8 NS 1.0
PlGF 69 84 78 NS 0.7 95 NS 0.2 71 NS 1.0 79 NS 0.7
VEGF-B 0 0 0   0   0   0  
VEGFR-1 67 92 50 NS 0.2 82 NS 0.4 59 NS 0.6 68 0.02
pVEGFR-1 Tyr1048 83 95 68 NS 0.3 91 NS 0.6 68 NS 0.2 80 NS 0.1
pVEGFR-1 Tyr1213 60 64 33 NS 0.1 50 NS 1.0 50 NS 0.6 56 NS 0.8
pVEGFR-1 Tyr1333 75 86 67 NS 0.5 68 NS 0.1 72 NS 1.0 68 NS 0.1
  1. z1 = zone 1, z2 = zone 2. p < 0.05 statistically significant. NS, not significant.