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Table 5 Numerical and percentage distribution of VEGFR-1/pVEGFR-1 co-expression tumor cells

From: Cell type- and tumor zone-specific expression of pVEGFR-1 and its ligands influence colon cancer metastasis

  N0/M0 n (%) N+ n (%) N0/M0 vs. N + p M+ n (%) N0/M0 vs. M + p
Co-expression in the tumor center
VEGFR-1+/pVEGFR-1Tyr1048+ 36/32 (89) 19/13 (68) NS 0.08 21/13 (62) 0.02
VEGFR-1+/pVEGFR-1Tyr1213+ 36/28 (78) 19/12 (63) NS 0.3 21/10 (48) 0.02
VEGFR-1+/pVEGFR-1Tyr1333+ 36/22 (61) 19/9 (47) NS 0.4 21/10 (48) NS 0.4
Co-expression in tumor budding regions
VEGFR-1+/pVEGFR-1Tyr1048 + 26/25 (96) 19/13 (68) 0.02 22/14 (64) 0.005
VEGFR-1+/pVEGFR-1Tyr1213 + 26/21 (81) 19/9 (47) 0.02 22/11 (50) 0.01
VEGFR-1+/pVEGFR-1Tyr1333 + 26/13 (50) 19/9 (47) NS 1.0 22/9 (41) NS 0.6
  1. n: total number of VEGFR-1 positive cases/total number of pVEGFR-1 positive cases with concomitant VEGFR-1 positivity. p < 0.05 statistically significant, NS not significant.