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Table 3 Reliability for interobserver variability of various measurements on MRI

From: A new relative tumor sizing method in epi-metaphyseal osteosarcoma

 

Mean ± SD

Interclass correlation (95% CI)

P

 

Observer 1

Observer 2

Observer 3

At diagnosis

RBS (mm)

53.40

52.67

54.70

0.947

<0.001

 

±24.38

±24.06

±24.49

(0.905 to 0.972)

 

ATL (mm)

99.27

94.12

92.24

0.909

<0.001

 

±66.31

±67.84

±65.00

(0.840 to 0.952)

 

ATA (mm)

49.23

55.74

41.24

0.725

<0.001

 

±20.93

±49.94

±16.19

(0.509 to 0.855)

 

TAR

1.00

0.95

0.82

0.807

<0.001

 

±0.31

±0.36

±0.23

(0.652 to 0.899)

 

After Neoadjuvant Chemotherapy

RBS (mm)

65.75

62.64

65.38

0.965

<0.001

 

±20.84

±22.16

±21.02

(0.942 to 0.979)

 

ATL (mm)

103.55

100.05

104.83

0.965

<0.001

 

±61.73

±63.58

±62.41

(0.944 to 0.979)

 

ATA (mm)

50.18

53.24

46.91

0.775

<0.001

 

±17.64

±26.16

±17.49

(0.640 to 0.865)

 

TAR

0.86

0.99

0.79

0.862

<0.001

 

±0.38

±0.50

±0.30

(0.775 to 0.919)

 
  1. Abbreviations: SD standard deviation, CI confidence interval, RBS reference bone axial size, ATL absolute tumor length, ATA absolute tumor axial size.