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Table 5 Conditional logistic regression model

From: The DNA load of six high-risk human papillomavirus types and its association with cervical lesions

HPV type

Viral load

With CIN / without CIN

Crude OR (95%CI)

Adjusted OR*

95%CI

HPV-16

Negative

25/62

Reference

  

0 < VL ≤ 5.86

12/13

2.19 (0.88–5.43)

3.53

1.1610.74

5.86 < VL

22/39

1.27 (0.64–2.50)

2.63

1.096.36

HPV-18

Negative

18/38

Reference

  

0 < VL ≤ 5.95

10/18

1.14 (0.45–2.89)

1.72

0.52–5.69

5.95 < VL

31/58

1.06 (0.52–2.17)

1.77

0.68–4.63

HPV-31

Negative

40/62

Reference

  

0 < VL ≤ 5.14

1/3

0.52 (0.04–6.29)

0.15

0.01–2.26

5.14 < VL

18/49

0.60 (0.32–1.14)

0.34

0.150.78

HPV-33

Negative

54/105

Reference

  

0 < VL ≤ 4.60

0/1

0.00 (0 - .)

0

0 - .

4.60 < VL

5/8

1.43 (0.45–4.50)

1.67

0.44–6.28

HPV-45

Negative

36/70

Reference

  

0 < VL ≤ 5.98

9/10

1.53 (0.60–3.92)

2.94

0.92–9.44

5.98 < VL

14/34

0.79 (0.38–1.67)

1.13

0.43–2.96

HPV-58

Negative

42/75

Reference

  

0 < VL ≤ 5.97

7/16

0.83 (0.32–2.11)

0.73

0.23–2.31

5.97 < VL

10/23

0.83 (0.37–1.83)

0.86

0.35–2.12

HR-HPV **

Negative

4/10

Reference

  

0 < VL ≤ 5.94

8/12

1.73 (0.40–7.47)

1.01

0.23–4.50

5.94 < VL

47/92

1.18 (0.35–4.00)

1.39

0.25–7.81

  1. Values in bold = p < 0.05.
  2. *Adjusted for origin, ethnicity, age at first intercourse and number of viral types.
  3. **HR-HPV: high-risk-human papillomavirus, infection by at least one high-risk viral type from the 6 analysed here (viral load = sum of viral loads of HPV types detected/ number of HPV types detected.
  4. HPV: human papillomavirus; CIN: cervical intraepithelial neoplasia; VL: viral load; OR: odds ratio.