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Table 4 Distribution of 6 HR-HPV types’ viral load regarding biopsy results

From: The DNA load of six high-risk human papillomavirus types and its association with cervical lesions

Viral type Negative (n = 28) CIN 1 (n = 16) CIN 2+ (n = 1)
% (n) Viral load, median (IQR) % (n) Viral load, median (IQR) % (n) Viral load, median (IQR)
Absolute Normalised* Absolute Normalised* Absolute Normalised*
HPV-16 66.67 (22) 6.42 (1.69) 1.79 (0.54) 57.89 (11) 6.77 (3.04) 1.69 (0.64) 0 n/a n/a
HPV-18 66.67 (22) 6.29 (1.34) 1.84 (0.51) 68.42 (13) 6.61 (2.28) 1.67 (1.79) 100 (1) 7.02 (n/a) 2.07 (n/a)
HPV-31 30.30 (10) 8.51 (1.90) 2.39 (0.38) 31.58 (6) 9.69 (6.00) 3.50 (2.17) 0 n/a n/a
HPV-33 3.03 (1) 6.75 (n/a) 1.98 (n/a) 10.53 (2) 8.48 (1.70) 2.37 (2.06) 100 (1) 10.57 (n/a) 3.13 (n/a)
HPV-45 51.52 (17) 6.13 (2.95) 1.79 (1.00) 42.11 (8) 6.24 (1.17) 1.61 (0.80) 0 n/a n/a
HPV-58 21.21 (7) 5.93 (3.89) 2.14 (2.35) 36.84 (7) 6.12 (0.34) 1.75 (0.28) 0 n/a n/a
HR-HPV** 94.34 (31) 6.37 (1.20) 2.06 (0.63) 94.74 (18) 6.77 (2.97) 2.12 (1.37) 100 (1) 8.80 (n/a) 2.60 (n/a)
  1. Absolute and normalised viral loads were both log10 transformed.
  2. *HPV copies/cell = number of HPV copies/(number of HMBS copies/2).
  3. **HR-HPV: high risk-human papillomavirus, infection by at least one high-risk viral type from the 6 analysed here.
  4. HPV: human papillomavirus; CIN: cervical intraepithelial neoplasia; CIN 1: cervical intraepithelial neoplasia 1; CIN 2+: cervical intraepithelial neoplasia 2 or 3; n/a: not applicable.
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