The DNA load of six high-risk human papillomavirus types and its association with cervical lesions

BMC Cancer

Table 3 Type-specific HR-HPV viral load distribution by category

HPV type	n	%	With CIN (n = 59)						Without CIN(n = 114)						p
			Negative		Low viral load		High viral load		Negative		Low viral load		High viral load
			n	%	n	%	n	%	n	%	n	%	n	%
HPV-16	86	49.71	25	42.37	12	20.34	22	37.29	62	54.39	13	11.40	39	34.21	0.186
HPV-18	117	67.63	18	30.51	10	16.95	31	52.54	38	33.33	18	15.79	58	50.88	0.928
HPV-31	71	41.04	40	67.80	1	1.69	18	30.51	62	54.39	3	2.63	49	42.98	0.257
HPV-33	14	8.09	54	91.53	0	0.00	5	8.47	105	92.11	1	0.88	8	7.02	0.846
HPV-45	67	38.73	36	61.02	9	15.25	14	23.73	70	61.40	10	8.77	34	29.82	0.366
HPV-58	56	32.37	42	71.19	7	11.86	10	16.95	75	65.79	16	14.04	23	20.18	0.772
HR-HPV ^*	159	91.91	4	6.78	8	13.56	47	79.66	10	8.77	12	10.53	92	80.70	0.777

HPV DNA load: categorised as ≤ 0 = negative. 0 < VL ≤ 10⁵ HPV copies = low viral load. >10⁵ HPV copies = high viral load.
^*HR-HPV: high risk-human papillomavirus, infection by at least one high-risk viral type from the 6 analysed here.
HPV: human papillomavirus; CIN: cervical intraepithelial neoplasia; p = p value.

ISSN: 1471-2407